How we grade

Full methodology page coming soon. Below is the short version — expect this to grow as the v1 database is built out.

We grade the molecule, not the brand.

Our unit of analysis is a molecule (e.g. creatine monohydrate), not a specific consumer product. Brands compete on price and quality; the molecule’s evidence base is the same regardless of who packaged it.

Inputs

Curated PubMed extraction of randomized controlled trials and meta-analyses.
Per-claim grades (e.g. creatine for strength vs. creatine for cognition).
Pharmacist review of every entry before it ships to users.

Trust signals on every grade

RCT count. How many randomized controlled trials inform the grade.
Dose alignment. Whether typical retail doses match the doses used in the studies that found an effect.
Effect size. How large the effect was when one was found.

Affiliate trust posture

When we link to a place to buy a molecule, we surface 3+ options. The grade lives on the molecule. The brand has no influence on the grade.

Disclaimers

Cognisantis an educational and lifestyle tool. We use language like “studies suggest” and “may support” on purpose — supplements are not drugs and we do not diagnose, treat, or cure any condition. Talk to your doctor before changing what you take.